“Resident Reminders”

Practice Guideline Highlights in Gastroenterology 

Gastrointestinal Bleeding 

q       Estimation and replacement of blood loss is the single most important aspect of care 

q       Baseline evaluation

ü      Question carefully about ASA and NSAIDs recognizing that use is often surreptitious and that complicated ulcer diatheses are invariably from NSAIDs

ü      Orthostatic vital signs unless pulse >120

ü      Rectal exam- Note: melena, hematochezia, color, or occult blood

ü      Hemogram, metabolic profile, protime

ü      All patients with GI bleeding should have a diagnostic nasogastric lavage, even if lower source suspected, even if varices are likely. Note: fresh or old (coffee grounds) blood 

q       Observation

ü      Mortality remains 8-10% despite recent advances and patients should be admitted to an intensive care unit.

ü      Consult Gastroenterology and Surgery

ü      Serial exam and hematocrit even 4-6 hours. Call GI if condition changes 

q       Treatment

ü      If likelihood of chronic liver disease, start octreotide 50ug IV bolus and 50ug IV infusion

ü      Acid modulation with IV proton pump inhibitor

ü      Endoscopic findings can be used to triage and plan care. If non-bleeding Mallory-Weiss tear or clean-based ulcer, re-bleeding rate is <3% and the patient can be discharged if eating and hemodynamically stable. If visible vessel, adherent clot, active bleeding or therapeutic endoscopy, the re-bleed rate is 50-75% and patients should be observed at least 72 hour 

References:
DiPalma JA.  Gastrointestinal Bleeding.  In:  Critical Care Medicine, J.M. Civetta, R.W. Taylor, R.R. Kirby, eds., Philadelphia: J.B. Lippencott Co., 3rd edition, 1997;pp 2033-2044. 

Laine L, etal.  Prospective Evaluation of Immediate vs. Delayed Refeeding and Prognostic Value of Endoscopy in Patients with Upper Gastrointestinal Hemorrhage.  Gastroenterology 1992;102:314-316.

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